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Series GSE232390 Query DataSets for GSE232390
Status Public on Sep 11, 2023
Title Analysis of gene expression changes in K562 erythroleukemia cells after erythroid differentiation caused by incubation in the presence hemin [RNA-Seq]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Expression of the clusters of rDNA genes influences pluripotency, but the underlying mechanisms are not known yet. The clusters shape inter-chromosomal contacts with numerous genes controlling differentiation in human cells. The fact suggests the possible role of these contacts in formation of 3D chromosomal structures and regulation of gene expression in development. We used human leukemia K562 cells induction to erythroid differentiation in order to study the changes in gene expression.
 
Overall design Comparative gene expression profiling analysis of RNA-seq data for K562 cells untreated and incubated for 108h with 50 μM concentration of hemin.
 
Contributor(s) Tchurikov NA, Kravatsky YV
Citation(s) 37372991
Submission date May 12, 2023
Last update date Sep 12, 2023
Contact name Nickolai Tchurikov
E-mail(s) tchurikov@eimb.ru
Organization name Engelhardt Institute of Molecular Biology
Department Department of Epigenetic Mechanisms of Gene Expression Regulation
Street address 32, Vavilova str.
City Moscow
ZIP/Postal code 119991
Country Russia
 
Platforms (1)
GPL18460 Illumina HiSeq 1500 (Homo sapiens)
Samples (4)
GSM7329821 RNA-Seq K562 WHITE rep1
GSM7329824 RNA-Seq K562 WHITE rep2
GSM7329826 RNA-Seq K562 RED rep1
This SubSeries is part of SuperSeries:
GSE232393 K562 erythroleukemia cells after erythroid differentiation caused by incubation in the presence of hemin
Relations
BioProject PRJNA971911

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE232390_K562.RED.FPKM.txt.gz 592.5 Kb (ftp)(http) TXT
GSE232390_K562.RED.TPM.txt.gz 599.9 Kb (ftp)(http) TXT
GSE232390_K562.WHITE.FPKM.txt.gz 595.3 Kb (ftp)(http) TXT
GSE232390_K562.WHITE.TPM.txt.gz 603.1 Kb (ftp)(http) TXT
GSE232390_RAW.tar 13.7 Mb (http)(custom) TAR (of RESULTS)
GSE232390_RNAseq.RED.forward.bw 41.9 Mb (ftp)(http) BW
GSE232390_RNAseq.RED.reverse.bw 41.9 Mb (ftp)(http) BW
GSE232390_RNAseq.WHITE.forward.bw 42.2 Mb (ftp)(http) BW
GSE232390_RNAseq.WHITE.reverse.bw 42.3 Mb (ftp)(http) BW
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
Processed data provided as supplementary file

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