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Series GSE232159 Query DataSets for GSE232159
Status Public on Nov 01, 2023
Title Comparison of T cell response to S. aureus and E. coli derived virulence determinants using RNA sequencing
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We aimed to compare transcriptomic changes in T cells in response to sterile bacterial culture supernatants derived from different E.coli and S.aureus strains. Gene expression was analyzed at two different time points.
Overall design Jurkat T cells were treated with sterile supernatants from bacterial overnight cultures or left untreated as control. Two S.aureus strains (USA300, ST398) and three E.coli strains (536, IHE3034, MG1655) were used. RNA was isolated 1h and 6h after exposure. Three biological replicates per treatment were included.
Contributor(s) vom Werth KL, Huge A, Kampmeier S, Mellmann A
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Submission date May 10, 2023
Last update date Nov 01, 2023
Contact name Kari Lavinia vom Werth
Organization name University Hospital Münster
Department Institute of Hygiene
Street address Robert-Koch-Str. 41
City Münster
ZIP/Postal code 48149
Country Germany
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (39)
GSM7316611 Ctrl, 0h, R1
GSM7316612 Ctrl, 0h, R2
GSM7316613 Ctrl, 0h, R3
BioProject PRJNA971149

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE232159_Deseq2_536_1h_vs_Ctrl_1h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_536_6h_vs_Ctrl_6h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_IHE3034_1h_vs_Ctrl_1h.txt.gz 5.3 Mb (ftp)(http) TXT
GSE232159_Deseq2_IHE3034_6h_vs_Ctrl_6h.txt.gz 5.3 Mb (ftp)(http) TXT
GSE232159_Deseq2_MG1655_1h_vs_Ctrl_1h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_MG1655_6h_vs_Ctrl_6h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_ST398_1h_vs_Ctrl_1h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_ST398_6h_vs_Ctrl_6h.txt.gz 5.2 Mb (ftp)(http) TXT
GSE232159_Deseq2_USA300_1h_vs_Ctrl_1h.txt.gz 5.3 Mb (ftp)(http) TXT
GSE232159_Deseq2_USA300_6h_vs_Ctrl_6h.txt.gz 5.3 Mb (ftp)(http) TXT
GSE232159_Raw_read_counts_All.txt.gz 1.6 Mb (ftp)(http) TXT
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Processed data are available on Series record

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