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| Status |
Public on Mar 31, 2024 |
| Title |
Aristolochic Acid Nephropathy 2 week time point of CD45+ cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
An evolutionarily conserved kidney resident macrophage phenotype defined by reduced MHCII expression universally appears after acute and chronic kidney injury
To investigate transcriptional and spatial differences in the MHC II negative kidney resident subpopualtion after CKD
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| Overall design |
Single cell RNA sequencing and spatial transcriptomic analysis to identify and visualize MHC II- kideny resident macrophages and CD4+ T cells, scRNAseq samples were hashed
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| Contributor(s) |
Erman EN, Moore KH, Cheung MD, La Fontaine JR, Yang Z, Soliman R, Aqarwal A, George JF |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Mar 29, 2023 |
| Last update date |
Apr 01, 2024 |
| Contact name |
James F George |
| E-mail(s) |
jfgeorge@uabmc.edu
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| Phone |
2059344261
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| Organization name |
University of Alabama at Birmingham
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| Street address |
1720 2nd Ave South
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| City |
Birmingham |
| State/province |
Alabama |
| ZIP/Postal code |
35294 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA950086 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE228516_AAWeek2.csv.gz |
355 b |
(ftp)(http) |
CSV |
| GSE228516_RAW.tar |
78.9 Mb |
(http)(custom) |
TAR (of CSV, H5, JPG, JSON, MTX, PNG, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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