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Series GSE22761 Query DataSets for GSE22761
Status Public on Jul 07, 2010
Title Expression data in Ischemia and Reperfusion during microsurgical tissue transfer
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Gene Expression of muscle tissue during microsurgical free tissue transfer was basicly studied in animal models. There was found activation of inflammatory and apoptotic cascades and of genes regulating intracellular metabolism.
We used microarrays to detail the programme of gene expression in human muscle tissue which is activated during this process.
Overall design Human muscle which was harvested during microsurgical free tissue transfer was used for RNA extraction and hybridization on Affymetrix microarrays. Muscle samples of the flap were taken during normoxia (I) after ischemia (II) and after reperfusion (III). Ischemia startet after dissecting the sustentative vessel. Reperfusion began after reanastomosing the vessel and restoring the blood supply.
Contributor(s) Dragu A, Schnürer S
Citation(s) 21617463
Submission date Jul 06, 2010
Last update date Dec 13, 2020
Contact name Stefan Schnürer
Organization name University of Erlangen-Nuremberg
Department Plastic and Handsurgery
Street address Schuhstr. 37
City Erlangen
ZIP/Postal code 91052
Country Germany
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (15)
GSM562839 patient 1, normoxia
GSM562840 patient 1, ischemia
GSM562841 patient 1, reperfusion
BioProject PRJNA128245

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Supplementary file Size Download File type/resource
GSE22761_RAW.tar 134.8 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table
Processed data provided as supplementary file

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