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GEO help: Mouse over screen elements for information. |
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| Status |
Public on May 11, 2023 |
| Title |
RNA-seq profiling of WT and LKB1 knockout mouse embryonic fibroblasts treated with the HAT inhibitor A485 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Investigating transcriptional profile of WT and LKB1 knockout mouse embryonic fibroblasts untreated, stimulated with IL-1β, treated with A485 alone, or stimulated with IL-1β and A485
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| Overall design |
RNA-seq was performed on WT and LKB1 knockout MEFs that were pre-treated with the HAT inhibitor A485 for 30 minutes prior to 6 hour vehicle or IL-1β treatment.
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| Contributor(s) |
Compton SE, Jones RG |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Mar 15, 2023 |
| Last update date |
May 13, 2023 |
| Contact name |
Russell Jones |
| E-mail(s) |
russell.jones@vai.org
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| Phone |
6166001610
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| Organization name |
Van Andel Institute
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| Street address |
333 Bostwick Ave. NE
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| City |
Grand Rapids |
| State/province |
MI |
| ZIP/Postal code |
49503 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (24)
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| GSM7100712 |
MEF, WT, A485, rep1 |
| GSM7100713 |
MEF, WT, A485, rep2 |
| GSM7100714 |
MEF, WT, A485, rep3 |
| GSM7100715 |
MEF, KO, ctrl, rep1 |
| GSM7100716 |
MEF, KO, ctrl, rep2 |
| GSM7100717 |
MEF, KO, ctrl, rep3 |
| GSM7100718 |
MEF, KO, A485, rep1 |
| GSM7100719 |
MEF, KO, A485, rep2 |
| GSM7100720 |
MEF, KO, A485, rep3 |
| GSM7100721 |
MEF, WT, IL1β, rep1 |
| GSM7100722 |
MEF, WT, IL1β, rep2 |
| GSM7100723 |
MEF, WT, IL1β, rep3 |
| GSM7100724 |
MEF, WT, A485+IL1β, rep1 |
| GSM7100725 |
MEF, WT, A485+IL1β, rep2 |
| GSM7100726 |
MEF, WT, A485+IL1β, rep3 |
| GSM7100727 |
MEF, KO, IL1β, rep1 |
| GSM7100728 |
MEF, KO, IL1β, rep2 |
| GSM7100729 |
MEF, KO, IL1β, rep3 |
| GSM7100730 |
MEF, KO, A485+IL1β, rep1 |
| GSM7100731 |
MEF, KO, A485+IL1β, rep2 |
| GSM7100732 |
MEF, KO, A485+IL1β, rep3 |
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| This SubSeries is part of SuperSeries: |
| GSE214824 |
WT, LKB1 KO, and LKB1/CRTC2 KO mouse embryonic fibroblasts |
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| Relations |
| BioProject |
PRJNA945063 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE227446_RAW.tar |
8.1 Mb |
(http)(custom) |
TAR (of TAB) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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