GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE226873 Query DataSets for GSE226873
Status Public on Mar 17, 2023
Title Cleavage Under Targets and Release Using Nuclease (CUT&RUN) assay of glucocorticoid receptor (NR3C1) in aggressive B-cell lymphomas [JC3]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We determined that glucocorticoid treatment (prednisolone) affects oncogenic signaling in aggressive B-cell lymphomas. We sought to identify genes directly controlled and bound by NR3C1.
Overall design CUT and RUN assay to NR3C1-bound regions in HBL1, SUDHL5, FL318, RAMOS cells treated with DMSO or prednisolone (10mM for HBL1, FL318, RAMOS or 25nm for SUDHL5) for 2h and 18h.
Contributor(s) Choi J, Staudt LM
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Mar 07, 2023
Last update date Mar 19, 2023
Contact name David Huang
Organization name National Cancer Institute
Street address 9000 Rockville Pike
City Bethesda
State/province Maryland
ZIP/Postal code 20892-0001
Country USA
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (21)
GSM7086197 HBL1_PR_0h_bio replicate 1
GSM7086198 HBL1_PR_2h_bio replicate 1
GSM7086199 HBL1_PR_18h_bio replicate 1
This SubSeries is part of SuperSeries:
GSE225858 Targeting oncogenic BCR signaling therapeutically by glucocorticoids and CSK inhibition
BioProject PRJNA941917

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE226873_RAW.tar 36.4 Mb (http)(custom) TAR (of WIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap