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Series GSE226862 Query DataSets for GSE226862
Status Public on Mar 17, 2023
Title RNA sequencing/Gene expression studies of prednisolone in aggressive B-cell lymphomas [JC1]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We determined that glucocorticoid (prednisolone) treatment affects oncogenic signaling in aggressive B-cell lymphomas. We sought to measure gene expression change in aggressive B-cell lymphoma cells by RNA-sequencing following prednisolone treatment.
Overall design HBL1, BL60, MD8, FL318, SUDHL5 and RAMOS cells were treated in duplicates with DMSO or 10 ┬ÁM prednisolone for all cells except SUDHL5 with 25nm prednisolone for 6h and 24h.
Contributor(s) Choi J, Staudt LM
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Submission date Mar 07, 2023
Last update date Sep 26, 2023
Contact name David Huang
Organization name National Cancer Institute
Street address 9000 Rockville Pike
City Bethesda
State/province Maryland
ZIP/Postal code 20892-0001
Country USA
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (36)
GSM7086010 SUDHL5_0h_DMSO_Replicate 1
GSM7086011 SUDHL5_6h_Prednisolone_Replicate 1
GSM7086012 SUDHL5_24h_Prednisolone_Replicate 1
This SubSeries is part of SuperSeries:
GSE225858 Targeting oncogenic BCR signaling therapeutically by glucocorticoids and CSK inhibition
BioProject PRJNA941904

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE226862_DLBCL_Prednisolone_RNAseq_Normalized_Log2.txt.gz 1.5 Mb (ftp)(http) TXT
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