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Series GSE226862 Query DataSets for GSE226862
Status Public on Mar 17, 2023
Title RNA sequencing/Gene expression studies of prednisolone in aggressive B-cell lymphomas [JC1]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We determined that glucocorticoid (prednisolone) treatment affects oncogenic signaling in aggressive B-cell lymphomas. We sought to measure gene expression change in aggressive B-cell lymphoma cells by RNA-sequencing following prednisolone treatment.
 
Overall design HBL1, BL60, MD8, FL318, SUDHL5 and RAMOS cells were treated in duplicates with DMSO or 10 ┬ÁM prednisolone for all cells except SUDHL5 with 25nm prednisolone for 6h and 24h.
 
Contributor(s) Choi J, Staudt LM
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Submission date Mar 07, 2023
Last update date Sep 26, 2023
Contact name David Huang
Organization name National Cancer Institute
Street address 9000 Rockville Pike
City Bethesda
State/province Maryland
ZIP/Postal code 20892-0001
Country USA
 
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (36)
GSM7086010 SUDHL5_0h_DMSO_Replicate 1
GSM7086011 SUDHL5_6h_Prednisolone_Replicate 1
GSM7086012 SUDHL5_24h_Prednisolone_Replicate 1
This SubSeries is part of SuperSeries:
GSE225858 Targeting oncogenic BCR signaling therapeutically by glucocorticoids and CSK inhibition
Relations
BioProject PRJNA941904

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE226862_DLBCL_Prednisolone_RNAseq_Normalized_Log2.txt.gz 1.5 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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