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Series GSE226617 Query DataSets for GSE226617
Status Public on Mar 12, 2023
Title Saturating mutagenesis of the GADD45A intron 3 enhancer using STARRseq
Organisms Homo sapiens; synthetic construct
Experiment type Other
Summary Assessment of individual nucleotide impact on overall GADD45A enhancer activity, dependency on p53 and/or activation through inegrated stress response (ISR).
Overall design Massively parallel reporter assay (MPRA) testing every nucleotide substitution or deletion within the GADD45A intron 3 enhancer
Contributor(s) Sammons MA, Baniulyte G
Citation(s) 36993734
Submission date Mar 03, 2023
Last update date Apr 04, 2023
Contact name Morgan A Sammons
Organization name University at Albany - SUNY
Department Biological Sciences
Lab Sammons
Street address 1400 Washington Ave, Life Sciences 2075
City Albany
State/province NY
ZIP/Postal code 12222
Country USA
Platforms (2)
GPL30173 NextSeq 2000 (Homo sapiens)
GPL32628 NextSeq 2000 (synthetic construct)
Samples (7)
GSM7080408 RNA, GADD45A_enh_STARRSeq, HCT116, DMSO
GSM7080409 RNA, GADD45A_enh_STARRSeq, HCT116, Nutlin-3A
GSM7080410 RNA, GADD45A_enh_STARRSeq, HCT116, Tunicamycin
BioProject PRJNA940815

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE226617_GADD45A_enh_STARRSeq_raw_read_count.csv.gz 22.7 Kb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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