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Series GSE226516 Query DataSets for GSE226516
Status Public on Dec 12, 2023
Title Effect of subchronic ototoxic (3,3'-iminodipropionitrile - IDPN) exposure on the vestibular ganglion of the rat.
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Summary The response of the vestibular ganglion neurons to the stress or loss of their presynaptic hair cells (HC) is not understood. This understanding is necessary because the survival and functional competence of these neurons will determine the outcome of any intervention aiming at repair or regeneration of the HC. One existing observation is that of uncoupling of the synapse between the HCs and ganglion neurons following subchronic ototoxic exposure in rodent models. We here studied the expression response of the vestibular ganglion associated with this synaptic uncoupling.
Overall design Comparative gene expression profiling analysis of RNA-seq data from vestibular ganglia of control rats and rats after subchronic ototoxic exposure.
Contributor(s) Greguske EA, Maroto AF, Gut M, Esteve-Codina A, Barrallo-Gimeno A, Llorens J
Citation(s) 37100209
Submission date Mar 02, 2023
Last update date Dec 12, 2023
Contact name Jordi Llorens
Phone 34934024277
Organization name Universitat de Barcelona
Department Ciències Fisiològiques
Lab 4106
Street address Feixa Llarga s/n
City Hospitalet de Llobregat
State/province Catalunya
ZIP/Postal code 08907
Country Spain
Platforms (1)
GPL14844 Illumina HiSeq 2000 (Rattus norvegicus)
Samples (6)
GSM7078270 R00965LF_Control
GSM7078271 R00965NM_Control
GSM7078272 R00968RF_Control
This SubSeries is part of SuperSeries:
GSE226517 Effect of subchronic ototoxicity on the vestibular ganglion in rodents
BioProject PRJNA940465

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE226516_COUNTS_genes_LLORENS_03.txt.gz 500.4 Kb (ftp)(http) TXT
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Processed data are available on Series record

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