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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Nov 10, 2023 |
| Title |
p53 suppresses MHC class II antigen presentation by the intestinal epithelium to protect intestinal stem cells upon radiation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the role of p53 in radiation-induced gastrointestinal syndrome, we performed gene expression profiling analysis using data obtained from RNA-seq of small intestine tissues from WT and p53-/- mice at 1 day post 12Gy total-body irradiation.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data of small intestine tissues from WT and p53-/- mice at 1 day post 12Gy total-body irradiation.
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| Contributor(s) |
Wang J, Chang C, Yang X, Zhou F, Liu J, Bargonetti J, Zhang L, Xie P, Feng Z, Hu W |
| Citation(s) |
38167344 |
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| Submission date |
Mar 01, 2023 |
| Last update date |
Jan 16, 2024 |
| Contact name |
Jianming Wang |
| E-mail(s) |
jw1102@cinj.rutgers.edu
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| Organization name |
Rutgers Cancer Institute of New Jersey
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| Street address |
195 Little Albany St
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| City |
NEW BRUNSWICK |
| State/province |
NJ |
| ZIP/Postal code |
08901 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA940152 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE226421_gene_count.xls.gz |
563.5 Kb |
(ftp)(http) |
XLS |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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