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Series GSE223999 Query DataSets for GSE223999
Status Public on Dec 01, 2023
Title Distinct gene expression signatures comparing latent tuberculosis infection with different routes of Bacillus Calmette-Guérin vaccination
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary RNA-Seq was utilized to provide an unbiased assessment of systemic and mucosal immunity using blood cells from LTBI subjects and recipients of ID and oral (PO) BCG.
Overall design BAL cell gene expression was evaluated after overnight culture in medium alone (baseline conditions), or with virulent Mtb strain H37Rv in patients with latent tuberculosis infection (LTBI) and in BCG-vaccinated (ID and PO groups) and Mtb/BCG-naive patients.
Contributor(s) Silver R, Hoft D, Storer C, Head R
Citation(s) 38129388
Submission date Jan 29, 2023
Last update date Jan 02, 2024
Contact name Richard Silver
Organization name Case Western Reserve University and the Louis Stokes Cleveland VA Medical Center
Department Division of Pulmonary, Critical Care and Sleep Medicine
Street address 10900 Euclid Ave
City Cleveland
State/province OH
ZIP/Postal code 44106
Country USA
Platforms (1)
GPL21290 Illumina HiSeq 3000 (Homo sapiens)
Samples (54)
GSM7009632 patient N171, uninfected_in_vitro, control_group
GSM7009633 patient P060, uninfected_in_vitro, ltbi_group
GSM7009634 patient P061, uninfected_in_vitro, ltbi_group
BioProject PRJNA929281

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Supplementary file Size Download File type/resource
GSE223999_BAL_all.gene_CPM.txt.gz 8.8 Mb (ftp)(http) TXT
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