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Status |
Public on Feb 02, 2023 |
Title |
GZ21T inhibits the growth of actinic keratoses in a UVB induced model of skin carcinogenesis |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To investigate the mechanism behind GZ21T's ability to inhibit actinic keratoses growth in an ultra-violet B induced model of skin carcinogenisis
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Overall design |
Comparative gene expression profiling analysis of RNA-seq data for lesional, peri-lesional, non-lesional, and non-UV exposed skin of control and GZ21T treated SKH1 mice
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Contributor(s) |
Kwatra SG, Kwatra MM, Bordeaux ZA |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
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Submission date |
Jan 29, 2023 |
Last update date |
Feb 02, 2023 |
Contact name |
Zachary Bordeaux |
E-mail(s) |
zasxd3644@gmail.com
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Organization name |
Johns Hopkins
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Department |
Dermatology
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Street address |
206 1550 Orleans Street
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City |
Baltimore |
State/province |
MD |
ZIP/Postal code |
21231 |
Country |
USA |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (15)
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GSM7009271 |
Control 1, non-UV exposed |
GSM7009272 |
Control 2, lesional |
GSM7009273 |
Control 2, Peri-lesional |
GSM7009274 |
Control 2, non-lesional |
GSM7009275 |
Control 2, non-UV exposed |
GSM7009276 |
Control 3, lesional |
GSM7009277 |
Control 3, Peri-lesional |
GSM7009278 |
Control 3, non-lesional |
GSM7009279 |
Control 3, non-UV exposed |
GSM7009280 |
GZ21T 1, lesional |
GSM7009281 |
GZ21T 2, lesional |
GSM7009282 |
GZ21T 3, lesional |
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Relations |
BioProject |
PRJNA929265 |
Supplementary file |
Size |
Download |
File type/resource |
GSE223986_controlback_vs_controlnonles_genes_DESeq2.txt.gz |
568.0 Kb |
(ftp)(http) |
TXT |
GSE223986_controllesional_vs_GZlesional_genes_DESeq2.txt.gz |
586.7 Kb |
(ftp)(http) |
TXT |
GSE223986_controlnonles_vs_controlperiles_genes_DESeq2.txt.gz |
572.6 Kb |
(ftp)(http) |
TXT |
GSE223986_controlperiles_vs_contorllesional_genes_DESeq2.txt.gz |
617.7 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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