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Series GSE22385 Query DataSets for GSE22385
Status Public on Aug 08, 2010
Title Gene profiling: U87 IRE1 dominant negative cells vs. U87ctrl cells in culture
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptome analysis was performed from human U87 glioblastoma cell clones: U87 IRE1.NCK DN (U87dn, IRE1 dominant negative) and U87 control (U87ctrl, empty plasmid). Cells were grown in DMEM supplemented with 10% FBS and glutamine for 16 hours in culture prior mRNA isolation and analyses
Overall design U87dn cells expressing a dominant negative transgene of IRE1alpha were compared to U87ctrl cells transfected with the corresponding empty plamid to identify genes associated to tumor invasion and angiogenesis.
Contributor(s) Auf G, Jabouille A, Bouchecareilh M, Chevet E, Bikfalvi A, Moenner M
Citation(s) 20702765, 24330607
Submission date Jun 16, 2010
Last update date Feb 05, 2020
Contact name Michel Moenner
Phone 33 540008925
Fax 33 540008705
Organization name Inserm U920
Department Université Bordeaux 1
Lab Molecular Mechanisms of Angiogensis
Street address Avenue des Facultés
City Talence
ZIP/Postal code 33405
Country France
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (6)
GSM556719 U87 IRE1dn cells replicate 1
GSM556732 U87 IRE1dn cells replicate 2
GSM556746 U87 IRE1dn cells replicate 3
BioProject PRJNA127735

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Supplementary file Size Download File type/resource
GSE22385_RAW.tar 13.2 Mb (http)(custom) TAR (of CEL, CHP)
Processed data included within Sample table

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