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Status |
Public on Jun 03, 2024 |
Title |
Investigating the factors that regulate dengue virus infection in Aedes aegypti female mosquitoes with Aedes aegypti transcriptomic analysis |
Organism |
Aedes aegypti |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Understanding the molecular determinants of the mosquitoes’ competence to host the viruses holds promise to prevent their transmission. We performed transcriptomic analysis with data obtained from RNA-seq of dengue- or naïve- infected mosquitoes on day 1, 2, and 7 post infections
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Overall design |
Based on the gene expression profile of RNA-seq analysis, we compared different days of the gene expression ratio between dengue and naïve infection. The different groups of transcripts were clustered and were analyzed with KEGG pathway analysis.
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Contributor(s) |
Huang Y, Lee K, Shiao S, Chen C, Yu G, Yu M |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
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Submission date |
Jan 13, 2023 |
Last update date |
Jun 03, 2024 |
Contact name |
Yu-Ning Huang |
E-mail(s) |
wendy.h.8514@gmail.com
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Organization name |
National Taiwan University
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Department |
Biochemistry and molecular biology
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Street address |
No.1 Jen Ai road section 1
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City |
Taipei |
ZIP/Postal code |
100 |
Country |
Taiwan |
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Platforms (1) |
GPL28657 |
Illumina NovaSeq 6000 (Aedes aegypti) |
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Samples (18)
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GSM6934668 |
Aedes aegypti, Dengue-infected, Day1, Rep1 |
GSM6934669 |
Aedes aegypti, Dengue-infected, Day1, Rep2 |
GSM6934670 |
Aedes aegypti, Dengue-infected, Day1, Rep3 |
GSM6934671 |
Aedes aegypti, Dengue-infected, Day2, Rep1 |
GSM6934672 |
Aedes aegypti, Dengue-infected, Day2, Rep2 |
GSM6934673 |
Aedes aegypti, Dengue-infected, Day2, Rep3 |
GSM6934674 |
Aedes aegypti, Dengue-infected, Day7, Rep1 |
GSM6934675 |
Aedes aegypti, Dengue-infected, Day7, Rep2 |
GSM6934676 |
Aedes aegypti, Dengue-infected, Day7, Rep3 |
GSM6934677 |
Aedes aegypti, Naïve-infected, Day1, Rep1 |
GSM6934678 |
Aedes aegypti, Naïve-infected, Day1, Rep2 |
GSM6934679 |
Aedes aegypti, Naïve-infected, Day1, Rep3 |
GSM6934680 |
Aedes aegypti, Naïve-infected, Day2, Rep1 |
GSM6934681 |
Aedes aegypti, Naïve-infected, Day2, Rep2 |
GSM6934682 |
Aedes aegypti, Naïve-infected, Day2, Rep3 |
GSM6934683 |
Aedes aegypti, Naïve-infected, Day7, Rep1 |
GSM6934684 |
Aedes aegypti, Naïve-infected, Day7, Rep2 |
GSM6934685 |
Aedes aegypti, Naïve-infected, Day7, Rep3 |
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Relations |
BioProject |
PRJNA923715 |
Supplementary file |
Size |
Download |
File type/resource |
GSE222893_Day1_DENV_vs_Naive_D1_vs_N1_.xlsx |
4.3 Mb |
(ftp)(http) |
XLSX |
GSE222893_Day2_DENV_vs_Naive_D2_vs_N2_.xlsx |
4.0 Mb |
(ftp)(http) |
XLSX |
GSE222893_Day7_DENV_vs_Naive_D7_vs_N7_.xlsx |
4.0 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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