|
| Status |
Public on Aug 19, 2010 |
| Title |
Female human iPS cells retain an inactive X-chromosome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled expressed XIST RNA which is an indicator of an inactive X chromosome. Genes on the X-chromosome were also analyzed for overall levels of gene expression compared to human fibroblasts.
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| |
|
| Overall design |
hiPSC lines were generated and extracted for RNA with TriZOL and hybridization on Affymetrix arrays.
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| |
|
| Contributor(s) |
Tchieu J, Plath K |
| Citation(s) |
20727844 |
| |
| Submission date |
Jun 09, 2010 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Kathrin Plath |
| Organization name |
UCLA
|
| Department |
Biological Chemistry
|
| Lab |
BSRB 390B
|
| Street address |
615 Charles E. Young Drive South
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90095-1737 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (13)
|
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| Relations |
| BioProject |
PRJNA128759 |
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