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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 01, 2024 |
| Title |
Cellular composition of murine mitral valves during autoimmune valvular carditis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To characterize the cell types that compose the mitral valve during the development of autoimmune valvular carditis, we utilized scRNA sequencing. Live cells from inflamed valves of K/B.g7 mice or uninflamed B.g7 controls were collected and analyzed at 3-, 8-, and 25 weeks of age.
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| Overall design |
Live single cells were sorted from digested mitral valves using fluorescence-activated cell sorting (FACS) and analyzed using scRNA sequencing.
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| Contributor(s) |
Bryce A B, Lee A M, Jennifer L A, Maria M F, Konstantin Z, Amritha Y, Victoria O, Jessica L F |
| Citation(s) |
38269589 |
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| Submission date |
Dec 16, 2022 |
| Last update date |
Apr 01, 2024 |
| Contact name |
Bryce A Binstadt |
| E-mail(s) |
binstadt@umn.edu
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| Organization name |
University of Minnesota
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| Department |
Pediatrics
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| Street address |
2-200 WMBB Bench 8
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| City |
Minneapolis |
| State/province |
Minnesota |
| ZIP/Postal code |
55455 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA913174 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE221197_RAW.tar |
339.1 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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