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| Status |
Public on Jul 15, 2024 |
| Title |
Bulk Omni-ATAC-seq in young (2 months) and aged (22-24 months) mice across 23 cell-types |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To understand how age rewires the chromatin accessibility landscape, we molecularly profiled 23 purified cell types from 11 tissues and organs by assessing the cumulative signature of 15-25 young and aged mice for robust difference detection.
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| Overall design |
We performed Omni-ATAC-seq for young (2 months) and aged (22-24 months) mice for FACS sorted cell-types. For sequencing of libraries derived from primary cell samples the DNBSEQ-G400 instrument (Bejing Genomics Institute) was used for ATAC-seq libraries (100 bp paired end mode).
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| Contributor(s) |
Naval-Sanchez M, Patrick R, Depanhe N, Nefzger C |
| Citation(s) |
38959897 |
| |
| Submission date |
Dec 15, 2022 |
| Last update date |
Jul 16, 2024 |
| Contact name |
Christian Nefzger |
| Organization name |
The University of Queensland
|
| Department |
Institute for Molecular Biology
|
| Lab |
Cellular Reprogramming and Ageing
|
| Street address |
306 Carmody Road
|
| City |
Brisbane |
| State/province |
Queensland |
| ZIP/Postal code |
4067 |
| Country |
Australia |
| |
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| Platforms (1) |
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| Samples (166)
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| This SubSeries is part of SuperSeries: |
| GSE223050 |
The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1–linked chromatin opening |
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| Relations |
| BioProject |
PRJNA912643 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE221034_Adipocytes.bed.gz |
993.3 Kb |
(ftp)(http) |
BED |
| GSE221034_Adipocytes_aged_3_scpm.bed.gz |
814.7 Kb |
(ftp)(http) |
BED |
| GSE221034_Adipocytes_young_3_scpm.bed.gz |
617.3 Kb |
(ftp)(http) |
BED |
| GSE221034_B-cells.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_B-cells_aged_1_scpm.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_B-cells_young_1_scpm.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_Beta-cells.bed.gz |
1.7 Mb |
(ftp)(http) |
BED |
| GSE221034_Beta-cells_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Beta-cells_young_1_scpm.bed.gz |
1.5 Mb |
(ftp)(http) |
BED |
| GSE221034_Brain-endothelial.bed.gz |
992.1 Kb |
(ftp)(http) |
BED |
| GSE221034_Brain-endothelial_aged_1_scpm.bed.gz |
851.8 Kb |
(ftp)(http) |
BED |
| GSE221034_Brain-endothelial_young_1_scpm.bed.gz |
900.7 Kb |
(ftp)(http) |
BED |
| GSE221034_CD4-Memory.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_CD4-Memory_aged_1_scpm.bed.gz |
996.5 Kb |
(ftp)(http) |
BED |
| GSE221034_CD4-Memory_young_1_scpm.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_CD4-Naive.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_CD4-Naive_aged_1_scpm.bed.gz |
886.2 Kb |
(ftp)(http) |
BED |
| GSE221034_CD4-Naive_young_1_scpm.bed.gz |
959.0 Kb |
(ftp)(http) |
BED |
| GSE221034_CD8-Memory.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_CD8-Memory_aged_1_scpm.bed.gz |
961.5 Kb |
(ftp)(http) |
BED |
| GSE221034_CD8-Memory_young_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_CD8-Naive.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_CD8-Naive_aged_1_scpm.bed.gz |
979.4 Kb |
(ftp)(http) |
BED |
| GSE221034_CD8-Naive_young_1_scpm.bed.gz |
1015.4 Kb |
(ftp)(http) |
BED |
| GSE221034_CD8-Virtual-Mem.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_CD8-Virtual-Mem_aged_1_scpm.bed.gz |
1.0 Mb |
(ftp)(http) |
BED |
| GSE221034_CD8-Virtual-Mem_young_1_scpm.bed.gz |
1.0 Mb |
(ftp)(http) |
BED |
| GSE221034_Fat-progenitors.bed.gz |
1.5 Mb |
(ftp)(http) |
BED |
| GSE221034_Fat-progenitors_aged_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Fat-progenitors_young_1_scpm.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_HSC.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_HSC_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_HSC_young_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Keratinocytes.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_Keratinocytes_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Keratinocytes_young_1_scpm.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_Kidney-endothelial.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_Kidney-endothelial_aged_1_scpm.bed.gz |
925.4 Kb |
(ftp)(http) |
BED |
| GSE221034_Kidney-endothelial_young_1_scpm.bed.gz |
1.0 Mb |
(ftp)(http) |
BED |
| GSE221034_Kidney-tubular.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_Kidney-tubular_aged_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Kidney-tubular_young_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Liver-progenitors.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Liver-progenitors_aged_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Liver-progenitors_young_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Lymph-endothelial.bed.gz |
1.1 Mb |
(ftp)(http) |
BED |
| GSE221034_Lymph-endothelial_aged_1_scpm.bed.gz |
965.3 Kb |
(ftp)(http) |
BED |
| GSE221034_Lymph-endothelial_young_1_scpm.bed.gz |
1.0 Mb |
(ftp)(http) |
BED |
| GSE221034_Lymph-fibroblasts.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_Lymph-fibroblasts_aged_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Lymph-fibroblasts_young_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Muscle-fibroblasts.bed.gz |
1.7 Mb |
(ftp)(http) |
BED |
| GSE221034_Muscle-fibroblasts_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Muscle-fibroblasts_young_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Neurons.bed.gz |
1.0 Mb |
(ftp)(http) |
BED |
| GSE221034_Neurons_aged_3_scpm.bed.gz |
811.7 Kb |
(ftp)(http) |
BED |
| GSE221034_Neurons_young_3_scpm.bed.gz |
907.3 Kb |
(ftp)(http) |
BED |
| GSE221034_RAW.tar |
47.3 Gb |
(http)(custom) |
TAR (of BED, BW, NARROWPEAK) |
| GSE221034_Satellite-stem-cells.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Satellite-stem-cells_aged_1_scpm.bed.gz |
1.3 Mb |
(ftp)(http) |
BED |
| GSE221034_Satellite-stem-cells_young_1_scpm.bed.gz |
1.2 Mb |
(ftp)(http) |
BED |
| GSE221034_Skin-fibroblasts.bed.gz |
1.7 Mb |
(ftp)(http) |
BED |
| GSE221034_Skin-fibroblasts_aged_1_scpm.bed.gz |
1.5 Mb |
(ftp)(http) |
BED |
| GSE221034_Skin-fibroblasts_young_1_scpm.bed.gz |
1.5 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-epithelial.bed.gz |
1.9 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-epithelial_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-epithelial_young_1_scpm.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-fibroblasts.bed.gz |
1.6 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-fibroblasts_aged_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_Thymic-fibroblasts_young_1_scpm.bed.gz |
1.4 Mb |
(ftp)(http) |
BED |
| GSE221034_universal-matrix.counts.txt.gz |
78.5 Mb |
(ftp)(http) |
TXT |
| GSE221034_universal-matrix.gtf.gz |
8.5 Mb |
(ftp)(http) |
GTF |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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