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Status |
Public on Dec 31, 2024 |
Title |
scRNA-seq of total mouse aortic cells after CD8+ T cell depletion with CITE-seq and cell Hashing |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
scRNA-seq of aortic cells in atherosclerotic mice with CD8+ T cell depletion after establishment of atherosclerotic lesions
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Overall design |
We performed single-cell RNA-seq analysis with CITE-seq and cell hashing of total viable aortic cells from Ldlr-/- mice fed a high fat diet for 13 weeks and treated with a CD8 depleting antibody for the last 4 weeks of high fat diet
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Contributor(s) |
Cochain C, Arampatzi P, Saliba A, Zernecke A, Schäfer S |
Citation(s) |
38868941 |
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Submission date |
Dec 09, 2022 |
Last update date |
Jan 02, 2025 |
Contact name |
Antoine-Emmanuel Saliba |
E-mail(s) |
emmanuel.saliba@helmholtz-hzi.de
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Phone |
+49-931-31-81341
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Organization name |
Helmholtz Institute for RNA-based Infection Research
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Street address |
Josef-Schneider-Straße 2 / D15
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City |
Würzburg |
ZIP/Postal code |
97080 |
Country |
Germany |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (3) |
GSM6807097 |
Aortic Cells, anti-CD8 treatment, GEX [F9_2_GEX] |
GSM6807098 |
Aortic Cells, anti-CD8 treatment, ADT [F9_2_ADT] |
GSM6807099 |
Aortic Cells, anti-CD8 treatment, HTO [F9_2_HTO] |
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Relations |
BioProject |
PRJNA910470 |