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Series GSE21951 Query DataSets for GSE21951
Status Public on May 01, 2024
Title Regulation of c-Myc function by centromeric protein KLIP1
Organism Homo sapiens
Experiment type Expression profiling by array
Summary In this study, we show that the centromeric Kaposi’s sarcoma-associated herpesvirus (KSHV) latent nuclear antigen (LANA)-interacting protein 1 (KLIP1) is a novel regulator of the c-Myc pathway. A series of microarray experiments were designed to demonstrate that the expression levels of KLIP1 protein are inversely correlated with cell proliferation, and the expression of c-Myc targets.
Overall design 1 MCF7 parental cell, and 3 MCF7 cell clones with stable transfection of vector, and 4 MCF7 cell clones with stable transfection of KLIP1, all with 3 technical replicates were profiled with Phalanx microarrays to examine the differenetial expression due to the over-expression of KLIP1.
Contributor(s) Gao S, Kuhne K, Chen Y
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Submission date May 21, 2010
Last update date May 01, 2024
Contact name Yidong Chen
Phone 2105629163
Organization name UT Health Science Center at San Antonio
Department Population Health Sciences
Street address 8403 Floyd Curl Drive, MSC 7784
City San Antonio
State/province Texas
ZIP/Postal code 78229
Country USA
Platforms (1)
GPL6254 Phalanx Human OneArray
Samples (24)
GSM545892 Parental Cell, rep1
GSM545893 Parental Cell, rep2
GSM545894 Parental Cell, rep3
BioProject PRJNA127239

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Supplementary file Size Download File type/resource
GSE21951_RAW.tar 63.8 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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