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Series GSE218593 Query DataSets for GSE218593
Status Public on Jan 29, 2023
Title Spatial epigenome-transcriptome co-profiling of mammalian tissues
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We present spatially resolved high-spatial-resolution genome-wide co-mapping of epigenome and transcriptome by simultaneously profiling of chromatin accessibility and gene expression (spatial-ATAC-RNA-seq), as well as histone modification and gene expression (spatial-CUT&Tag-RNA-seq) on the same tissue section at cellular level by combining the microfluidic deterministic barcoding strategy in DBiT-seq and the chemistry used in ATAC-seq/CUT&Tag.
Overall design Spatially resolved co-sequencing of epigenome and transcriptome in mouse embryos and mouse brains.
Contributor(s) Fan R, Zhang D
Citation(s) 36922587
Submission date Nov 22, 2022
Last update date Apr 14, 2023
Contact name Di Zhang
Organization name Yale University
Department Biomedical Engineering
Street address 55 Prospect St
City New Haven
State/province CT
ZIP/Postal code 06511
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (6)
GSM6753041 MouseBrain_20um_repATAC
GSM6753042 MouseBrain_20um_H3K27ac rep
GSM6753043 MouseBrain_20um_100barcodes_ATAC
This SubSeries is part of SuperSeries:
GSE205055 Spatial epigenome-transcriptome co-profiling of mammalian tissues
BioProject PRJNA904377

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE218593_RAW.tar 141.8 Mb (http)(custom) TAR (of TAR, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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