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Series GSE218137 Query DataSets for GSE218137
Status Public on Aug 13, 2023
Title The role of DNMT3A in AITL
Platform organism Mus musculus
Sample organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Third-party reanalysis
Summary To investigate the role of DNMT3A in AITL, single cell RNA-seq (scRNA-seq) is performed to analysis the lymph nodes generated from the control, RHOAG17V and RHOAG17V DNMT3AR882H AITL mice. The mitoQC maps shows the distributions of unique gene detected and mitochondrial genes detected in each single cell. After the quality control, a total of 23,805 cells (7576 of control, 7913 of RHOAG17V and 8316 of RHOAG17V DNMT3AR882H) are used for clustering and further analyzing
Overall design single-cell RNA-seq

This record includes re-analysis of all samples in GSE197188. Data processing description and re-analyzed data (GSE218137_AITL_patient.rds.gz) are available for download at the foot of this record.
Contributor(s) Pan X, Zheng J, Wang Z, Chen C, Liu Y
Citation(s) 37127775
Submission date Nov 16, 2022
Last update date Aug 29, 2023
Contact name Xaingyu Pan
Organization name Sichuan University
Department State Key Laboratory of Biotherapy, West China Hospital, Sihcuan University.
Lab Chen & Liu Lab
Street address No.17 Renming road section3
City Chengdu, Cihna
State/province Sichuan
ZIP/Postal code 610041
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (3)
GSM6735338 RHOAG17V
GSM6735339 Control
Reanalysis of GSM5910841
Reanalysis of GSM5910842
Reanalysis of GSM5910843
Reanalysis of GSM5910844
BioProject PRJNA902396

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE218137_AITL_mice_Only_B.rds.gz 180.8 Mb (ftp)(http) RDS
GSE218137_AITL_mice_Only_T.rds.gz 181.0 Mb (ftp)(http) RDS
GSE218137_AITL_mice_all.rds.gz 385.0 Mb (ftp)(http) RDS
GSE218137_AITL_patient.rds.gz 24.4 Mb (ftp)(http) RDS
GSE218137_RAW.tar 174.5 Mb (http)(custom) TAR (of TAR)
GSE218137_Re-analyzed_data_processing_description.txt.gz 337 b (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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