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Series GSE217936 Query DataSets for GSE217936
Status Public on Feb 07, 2023
Title Gene expression profiles of mouse ischemia-reperfusion liver zones with or without celastrol-treated.
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Hepatic ischemia-reperfusion (I/R) has long affected the success rate of liver transplant. Though zone-specific injury induced by I/R was observed, elaborated cellular and molecular mechanisms underlying the I/R injury pattern have not been revealed. Spatial transcriptomics analysis has great potential to uncover the mechanisms of liver I/R injury.
Overall design We evaluated the gene expression profile of different zones of mouse liver from sham group, 70% liver I/R group and celastrol-treated I/R group using DSP spatial transcriptomics analysis. 147 ROIs were sequenced totally.
Web link
Contributor(s) Xin J, Yang T, Wu X, Wu Y, Liu Y, Liu X, Jiang M, Gao W
Citation(s) 36804628
Submission date Nov 14, 2022
Last update date Feb 26, 2023
Contact name Jiaqi Xin
Organization name CCMU
Street address No.11 Xitoutiao outside You’anmen
City Beijing
ZIP/Postal code 100069
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (141)
GSM6730434 C1_002
GSM6730435 C2_003
GSM6730436 C3_004
BioProject PRJNA901430

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Supplementary file Size Download File type/resource
GSE217936_RAW.tar 8.9 Mb (http)(custom) TAR (of DCC)
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Raw data are available in SRA
Processed data provided as supplementary file

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