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| Status |
Public on Nov 27, 2023 |
| Title |
Short-term consumption of ultra-processed diets impairs the sense of smell and brain physiology [Brain] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Considering the present scenario of fast-paced life, the major shifts in eating culture in the last five decades, and the crucial role of smell in food intake, it is thus crucial to map and better understand the effects of ultra-processed diets - especially under short-term regimens - on our brain metabolism and sense of smell. To address this question, we used mice to investigate the effects of the short-term consumption of three diets varying in macronutrient composition and origin (one whole-grain-based and two ultra-processed synthetic diets) on the transcriptional profiles of the olfactory mucosa and different brain regions.
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| Overall design |
Comparative gene expression profiling analysis of mRNA-seq data from organs/tissues of mice submitted to High Fat Diet (HFD), Normal Chow Diet (NCD) or Synthetic Chow Diet (SCD).
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| Contributor(s) |
Makhlouf M, Kurian S, Saraiva L |
| Citation(s) |
37977411 |
| |
| Submission date |
Nov 12, 2022 |
| Last update date |
Jan 03, 2024 |
| Contact name |
Melanie Makhlouf |
| E-mail(s) |
mmakhlouf1@sidra.org
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| Organization name |
Sidra Medicine
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| Street address |
Al Gharrafa Street,
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| City |
Ar-Rayyan, Doha, |
| ZIP/Postal code |
PO Box 26999 |
| Country |
Qatar |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (40)
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| This SubSeries is part of SuperSeries: |
| GSE218162 |
Short-term consumption of ultra-processed diets impairs the sense of smell and brain physiology |
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| Relations |
| BioProject |
PRJNA900858 |
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