 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Nov 01, 2023 |
| Title |
Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| Web link |
https://pubmed.ncbi.nlm.nih.gov/37572321/
|
| |
|
| Citation(s) |
37572321 |
| |
| Submission date |
Nov 10, 2022 |
| Last update date |
Mar 13, 2024 |
| Contact name |
Xiangzheng Liu |
| E-mail(s) |
lxz19@mails.tsinghua.edu.cn
|
| Organization name |
Tsinghua University
|
| Street address |
Tsinghua University, Haidian District, Beijing
|
| City |
Beijing |
| ZIP/Postal code |
100084 |
| Country |
China |
| |
|
| Platforms (2) |
| GPL21273 |
HiSeq X Ten (Mus musculus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (20)
|
| GSM6725669 |
Normal pancreas, Paf1-KO H3K27ac Input |
| GSM6725670 |
normal pancreas, Rosa26 knockout rep1 |
| GSM6725671 |
normal pancreas, Rosa26 knockout rep2 |
| GSM6725672 |
normal pancreas, Paf1 knockout rep1 |
| GSM6725673 |
normal pancreas, Paf1 knockout rep2 |
| GSM6725674 |
PDAC cells, sgiPaf1-1, Paf1 KD Chromatin RNA-seq |
| GSM6725675 |
PDAC cells, sgiPaf1-2, Paf1 KD Chromatin RNA-seq |
| GSM6725676 |
PDAC cells, Random4841 control, Chromatin RNA-seq |
| GSM6725677 |
PDAC cells, Random9270 control, Chromatin RNA-seq |
| GSM6725683 |
PDAC cell, shMyc RNA-seq |
| GSM6725684 |
PDAC cell, shMyc,Paf1 knockdown RNA-seq-1 |
| GSM6725685 |
PDAC cell, shMyc RNA-seq-2 |
| GSM6725686 |
PDAC cell, shMyc,Paf1 knockdown RNA-seq-2 |
| GSM6725687 |
PDAC cell, shControl RNA-seq-1 |
| GSM6725688 |
PDAC cell, shControl Paf1 knockdown RNA-seq-1 |
| GSM6725689 |
PDAC cell, shControl RNA-seq-2 |
| GSM6725690 |
PDAC cell, shControl Paf1 knockdown RNA-seq-2 |
|
| This SuperSeries is composed of the following SubSeries:
|
| GSE217740 |
Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion due to R-loop accumulation I |
| GSE217741 |
Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion due to R-loop accumulation II |
| GSE217742 |
Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion due to R-loop accumulation III |
| GSE217744 |
Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion due to R-loop accumulation IV |
|
| Relations |
| BioProject |
PRJNA900247 |
|
|
|
|
 |
Less...
More...