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Series GSE21750 Query DataSets for GSE21750
Status Public on May 08, 2010
Title Expression data from mesothelial (LP9) and mesothelioma cells (HMESO) inhibited for extracellular-regulated kinase (ERK) 1, 2, or 5
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Extracellular-regulated kinases (ERK1/2 and 5) are known to play important roles in growth and drug resistance of various cancers. Here we show roles of inhibition of ERK1, ERK2, or ERK5 on gene expression profiles of epithelioid malignant mesothelioma (MM) cells (HMESO).
Overall design Untransfected human mesothelial cells (LP9), MM cells (HMESO) or HMESO cells stably transfected with shControl, shERK1, shERK2 , or shERK5 plasmids were used. Microarrays were performed on samples from 3 independent experiments. Each sample was analyzed on a separate array (3 independent biological replicates).
Contributor(s) Shukla A
Citation(s) 21159167, 23446998
Submission date May 07, 2010
Last update date Dec 06, 2018
Contact name Arti Shukla
Phone 802-656-8253
Organization name University of Vermont
Department Pathology
Lab 215 HSRF
Street address 89 Beaumont Avenue
City Burlington
State/province VT
ZIP/Postal code 05405
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (18)
GSM542312 Mesothelial cell line, rep1
GSM542313 Mesothelial cell line, rep2
GSM542314 Mesothelial cell line, rep3
BioProject PRJNA127339

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Supplementary file Size Download File type/resource
GSE21750_RAW.tar 39.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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