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Series GSE217368 Query DataSets for GSE217368
Status Public on Mar 10, 2023
Title Gene expression profile at single cell level of phagocytic myeloid cells in autochthonous lung cancer model
Organism Mus musculus
Experiment type Other
Expression profiling by high throughput sequencing
Summary Phagocytosis is a critical process undertaken by myeloid cells in the tumor microenvironment. We used single-cell RNA-seq (scRNAseq) to investigate molecular and cellular consequences of neoplastic cell engulfment using a tdTomato genetically engineered mouse model.
Overall design CD45-positive and CD45-negative populations from the lung tissue of SPC-creER KRAS-G12D mice were isolated by Fluorescence-activated cell sorting (FACS) analyzed using scRNAseq with antibody-based cell hashing.
Contributor(s) Lu DR, Gonzalez MA, Arias V, Li C, Tarbell KV, Winslow M
Citation(s) 36995340
Submission date Nov 05, 2022
Last update date Jun 09, 2023
Contact name Daniel R Lu
Organization name Amgen
Street address 750 Gateway Blvd, Suite 100
City South San Francisco
State/province CA
ZIP/Postal code 94080
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (20)
GSM6716128 tdTom-neg myeloid cells from tumor-bearing mice, rep 1, mRNA-derived cDNA
GSM6716129 tdTom-neg myeloid cells from tumor-bearing mice, rep 1, HTO-derived cDNA
GSM6716130 tdTom-neg myeloid cells from tumor-bearing mice, rep 2, mRNA-derived cDNA
BioProject PRJNA898629

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE217368_barcodes1.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes10.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes2.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes3.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes4.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes5.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes6.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes7.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes8.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_barcodes9.tsv.gz 18.5 Mb (ftp)(http) TSV
GSE217368_features1.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features10.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features2.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features3.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features4.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features5.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features6.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features7.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features8.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_features9.tsv.gz 244.8 Kb (ftp)(http) TSV
GSE217368_matrix1.mtx.gz 105.9 Mb (ftp)(http) MTX
GSE217368_matrix10.mtx.gz 57.9 Mb (ftp)(http) MTX
GSE217368_matrix2.mtx.gz 110.9 Mb (ftp)(http) MTX
GSE217368_matrix3.mtx.gz 42.8 Mb (ftp)(http) MTX
GSE217368_matrix4.mtx.gz 51.2 Mb (ftp)(http) MTX
GSE217368_matrix5.mtx.gz 5.5 Mb (ftp)(http) MTX
GSE217368_matrix6.mtx.gz 58.0 Mb (ftp)(http) MTX
GSE217368_matrix7.mtx.gz 55.2 Mb (ftp)(http) MTX
GSE217368_matrix8.mtx.gz 61.1 Mb (ftp)(http) MTX
GSE217368_matrix9.mtx.gz 48.0 Mb (ftp)(http) MTX
GSE217368_seurat_tdTom_allSamples_ForSubmission.rds.gz 705.4 Mb (ftp)(http) RDS
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Raw data are available in SRA
Processed data are available on Series record

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