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Series GSE213217 Query DataSets for GSE213217
Status Public on Sep 12, 2023
Title High concentration of adrenaline blocks key cell cycle genes and exhibits antifibrotic and vasoconstrictor effects in glaucoma surgery
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary To investigate the effects of adrenaline on fibrosis in glaucoma surgery. Human Tenon’s fibroblasts (HTFs) were treated with adrenaline (0%, 0.0005%, 0.01%) for 24 hours and RNA-Sequencing was performed on the Illumina NextSeq2000. We carried out detailed gene ontology, pathway, disease and drug enrichment analyses.
Overall design Comparative gene expression profiling analysis of RNA-seq data for HTFs treated with different concentrations of adrenaline (0%, 0.0005%, 0.01%).
Contributor(s) Yu-Wai-Man C
Citation(s) 37429521
Submission date Sep 12, 2022
Last update date Dec 13, 2023
Contact name Cynthia Yu-Wai-Man
Organization name King's College London
Street address Westminster Bridge Road
City London
ZIP/Postal code SE1 7EH
Country United Kingdom
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (9)
GSM6574554 Human Tenon's fibroblasts, Control 1, Day1
GSM6574555 Human Tenon's fibroblasts, Control 2, Day1
GSM6574556 Human Tenon's fibroblasts, Control 3, Day1
BioProject PRJNA879766

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Supplementary file Size Download File type/resource
GSE213217_Adrenaline0.0005_vsControl.complete.txt.gz 1.3 Mb (ftp)(http) TXT
GSE213217_Adrenaline0.01_vsAdrenaline0.0005_.complete.txt.gz 1.3 Mb (ftp)(http) TXT
GSE213217_Adrenaline0.01_vsControl.complete.txt.gz 1.3 Mb (ftp)(http) TXT
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