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| Status |
Public on May 09, 2023 |
| Title |
Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease [scATAC-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
In this study, we use single-cell ATAC sequencing (scATAC-seq) and single-cell RNA sequencing (scRNA-seq) to map chromatin accessibility and gene expression in human scalp samples from healthy patients and patients with alopecia areata
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| Overall design |
We generated single-cell ATAC-seq and single-cell RNA-seq libraries from human scalp tissue from three sources: punch biopsy samples from healthy control volunteers (C_PB, n = 3), punch biopsies from patients with clinically active alopecia areata (AA, n = 5), and discarded normal peripheral surgical tissue from patients undergoing dermatologic surgeries on the scalp (C_SD, n = 7)
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| Contributor(s) |
Ober-Reynolds B |
| Citation(s) |
37500727 |
| |
| Submission date |
Aug 31, 2022 |
| Last update date |
Aug 13, 2023 |
| Contact name |
Benjamin Ober-Reynolds |
| E-mail(s) |
boberrey@stanford.edu
|
| Organization name |
Stanford University
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| Department |
Genetics
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| Lab |
Greenleaf
|
| Street address |
279 Campus Drive West
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| City |
Stanford |
| State/province |
CA |
| ZIP/Postal code |
94305 |
| Country |
USA |
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| Platforms (1) |
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| Samples (13)
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| This SubSeries is part of SuperSeries: |
| GSE212450 |
Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease |
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| Relations |
| BioProject |
PRJNA875445 |
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