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Series GSE211684 Query DataSets for GSE211684
Status Public on Aug 30, 2023
Title Effect of CHOP, Selinexor or their combination on gene expression in a patient-derived xenograft model of DLBCL
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To determine how exposure to CHOP, Selinexor or their combination affects gene expression in DLBCL, we first established a patient-derived xenograft model of DLBCL.
Next, mice were randomized to receive either vehicle, CHOP, Selinexor or their combination. Tumors were harvested at the end of treatment and gene expression profile analyzed by RNA-sequencing.
Overall design Three replicates per treatment arm (vehicle, CHOP, Selinexor, CHOP + selinexor) were sequenced.
Contributor(s) Marullo R, Revuelta MV, Cerchietti L
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Submission date Aug 19, 2022
Last update date Aug 30, 2023
Contact name Maria Victoria Revuelta
Organization name Weill Cornell Medicine
Department Medicine
Street address 1300 York Avenue
City New York
State/province New York
ZIP/Postal code 10065
Country USA
Platforms (1)
GPL22245 Illumina HiSeq 2500 (Homo sapiens; Mus musculus)
Samples (12)
GSM6482986 CHOP1 human and mouse
GSM6482987 CHOP3 human and mouse
GSM6482988 CHOP5 human and mouse
BioProject PRJNA871300

Download family Format
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE211684_RAW.tar 962.9 Mb (http)(custom) TAR (of ZIP)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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