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Series GSE211373 Query DataSets for GSE211373
Status Public on Aug 21, 2022
Title RNA data of MKN45 tumours treated with ERY974 and/or capecitabine in huNOG mice
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We found that ERY974 shows only moderate antitumor efficacy in MKN45 non-inflamed tumor in huNOG mice. We also observed that ERY974 + capecitabine increases antitumour efficacy in non-inflamed MKN45 tumours.
To identify a mechanism of combination effect, we compared RNA expression of MKN45 tumors treated with ERY974, capecitabine, or combination.
Overall design Comparative gene expression profiling analysis of RNA-seq data for tumors treated with ERY974, capecitabine, or combination in huNOG model.
Contributor(s) Sano Y, Nishito Y, Azuma Y, Kinoshita Y, Tsunenari T, Ishiguro T
Citation(s) 36071036
Submission date Aug 16, 2022
Last update date Nov 21, 2022
Contact name YUJI SANO
Phone +810467476241
Organization name Chugai Pharmaceutical Co., Ltd
Street address 200
City Kajiwara
State/province Kamakura
ZIP/Postal code 247-8530
Country Japan
Platforms (2)
GPL22245 Illumina HiSeq 2500 (Homo sapiens; Mus musculus)
GPL25526 Illumina NovaSeq 6000 (Homo sapiens; Mus musculus)
Samples (24)
GSM6467639 MKN45_vehicle_1
GSM6467640 MKN45_vehicle_2
GSM6467641 MKN45_vehicle_3
BioProject PRJNA870059

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE211373_seq_combo_with_capecitabine.xlsx 111.2 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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