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Series GSE210180 Query DataSets for GSE210180
Status Public on May 17, 2024
Title Effect of neonatal right ventricular pressure overload on gene expression and regions of open chromatin during postnatal heart development
Organism Rattus norvegicus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary To investigate the effect of pressure overload (PO) during postnatal right ventricular (RV) development, we established the RV PO model by conducting pulmonary artery banding (PAB) surgery on neonatal Sprague-Dawley (SD) rats. We then performed gene expression and chromatin openness profiling analysis using data obtained from RNA-seq and ATAC-seq of RV free walls from PO and sham-operated rats at postnatal day 21 (P21).
 
Overall design Comparative gene expression and chromatin openness profiling analysis of RNA-seq and ATAC-seq data for right ventricular free wall myocardium in pressure overload and sham-operated Sprague-Dawley (SD) rats on postnatal day21.
 
Contributor(s) Hu Y, Li D, Ye L, Li F
Citation(s) 38666846
Submission date Aug 01, 2022
Last update date May 18, 2024
Contact name Yuqing Hu
E-mail(s) christy497@outlook.com
Organization name Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine
Street address 1678 Dongfang Road, Pudong New District, Shanghai
City Shanghai
ZIP/Postal code 200127
Country China
 
Platforms (1)
GPL25947 Illumina NovaSeq 6000 (Rattus norvegicus)
Samples (12)
GSM6423045 RV free wall, sham-operated, P21, RNA-seq, rep1
GSM6423046 RV free wall, sham-operated, P21, RNA-seq, rep2
GSM6423047 RV free wall, sham-operated, P21, RNA-seq, rep3
Relations
BioProject PRJNA864632

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE210180_RAW.tar 13.0 Mb (http)(custom) TAR (of TXT)
GSE210180_gene_fpkm.txt.gz 2.0 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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