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| Status |
Public on Dec 28, 2022 |
| Title |
Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the timing of endogenous regenerative events in response to a single 10 Gy dose of IR, we sequeced the transcriptomes of glands from adult (6-7 wks)mice and 7- and 14-days post-IR.
We then compared to the radiated glands to Non-IR (no radiation) controls, and performed differential expression analysis.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for Ct (Non-IR, no radiation control), IR7 (7 days post-radiation) and IR14 (14 days post-radiation) sublingual salivary glands.
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| Contributor(s) |
Li J, Sudiwala S, May A |
| Citation(s) |
36542703 |
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| Submission date |
Jul 27, 2022 |
| Last update date |
Dec 29, 2022 |
| Contact name |
Jianlong Li |
| E-mail(s) |
Jianlong.li@ucsf.edu
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| Phone |
585-386-9988
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| Organization name |
UCSF
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| Department |
Cell and Tissue Biology
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| Lab |
Knox
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| Street address |
513 Parnassus Avenue
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| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94143 |
| Country |
USA |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (9)
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| GSM6410764 |
Sublingual salivary gland, no radiation control 1 |
| GSM6410765 |
Sublingual salivary gland, no radiation control 2 |
| GSM6410766 |
Sublingual salivary gland, no radiation control 3 |
| GSM6410767 |
Sublingual salivary gland, 7 days post radiation 1 |
| GSM6410768 |
Sublingual salivary gland, 7 days post radiation 2 |
| GSM6410769 |
Sublingual salivary gland, 7 days post radiation 3 |
| GSM6410770 |
Sublingual salivary gland, 14 days post radiation 1 |
| GSM6410771 |
Sublingual salivary gland, 14 days post radiation 2 |
| GSM6410772 |
Sublingual salivary gland, 14 days post radiation 3 |
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| Relations |
| BioProject |
PRJNA862964 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE209931_RAW.tar |
1.9 Mb |
(http)(custom) |
TAR (of CSV) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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