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| Status |
Public on Jul 27, 2022 |
| Title |
Gene expression profile at single cell level of human cerebral organoid transplants harvested from the mouse brain. |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Transplanted human cerebal organoids were developed from induced pluripotent stem cells that were reprogrammed from human urine-contained epithelial cells. Immune-compromised mice with brain lesions caused by distal middle cerebral artery occlusion (dMCAO) were used as recipients for transplantation. The organoids were grafted at the lesion cavity. Each transplant sample was collected from the brain of a mouse, disassociated, and sequenced using a 10x Genomics single-cell RNA-sequencing platform.
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| Overall design |
Three tissue samples involved in this submitted single-cell RNA sequencing data set were human cerebral organoid transplants harvested from the mouse brain.
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| Contributor(s) |
Wang Y, Hu J, Bird JT, Byrum SD |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Jul 20, 2022 |
| Last update date |
Jul 29, 2022 |
| Contact name |
Yu-Chieh Wang |
| E-mail(s) |
yucwang@mcw.edu
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| Organization name |
Medical College of Wisconsin
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| Department |
Dermatology and Cancer
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| Lab |
Wang
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| Street address |
8701 Watertown Plank Rd.,
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| City |
Milwaukee |
| State/province |
WI |
| ZIP/Postal code |
53226 |
| Country |
USA |
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| Platforms (1) |
| GPL19415 |
Illumina NextSeq 500 (Homo sapiens; Mus musculus) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA860646 |
