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Series GSE208710 Query DataSets for GSE208710
Status Public on Jul 27, 2022
Title Gene expression profile at single cell level of human cerebral organoid transplants harvested from the mouse brain.
Organisms Homo sapiens; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Transplanted human cerebal organoids were developed from induced pluripotent stem cells that were reprogrammed from human urine-contained epithelial cells.  Immune-compromised mice with brain lesions caused by distal middle cerebral artery occlusion (dMCAO) were used as recipients for transplantation.  The organoids were grafted at the lesion cavity.  Each transplant sample was collected from the brain of a mouse, disassociated, and sequenced using a 10x Genomics single-cell RNA-sequencing platform.
Overall design Three tissue samples involved in this submitted single-cell RNA sequencing data set were human cerebral organoid transplants harvested from the mouse brain. 
Contributor(s) Wang Y, Hu J, Bird JT, Byrum SD
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Submission date Jul 20, 2022
Last update date Jul 29, 2022
Contact name Yu-Chieh Wang
Organization name Medical College of Wisconsin
Department Dermatology and Cancer
Lab Wang
Street address 8701 Watertown Plank Rd.,
City Milwaukee
State/province WI
ZIP/Postal code 53226
Country USA
Platforms (1)
GPL19415 Illumina NextSeq 500 (Homo sapiens; Mus musculus)
Samples (3)
GSM6364828 Wang1,scRNAseq
GSM6364829 Wang2,scRNAseq
GSM6364830 Wang3,scRNAseq
BioProject PRJNA860646

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Supplementary file Size Download File type/resource
GSE208710_RAW.tar 526.5 Mb (http)(custom) TAR (of MTX, TSV)
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Raw data are available in SRA
Processed data provided as supplementary file

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