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Series GSE206831 Query DataSets for GSE206831
Status Public on Jun 05, 2023
Title ORC1 binds to cis-transcribed RNAs for efficient activation of human origins [CDC45_ChIP-seq]
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary By investigating the RNA binding activity of human ORC1, we show that it interacts with RNAs transcribed at active origins, which is linked to ORC1 dynamic association to the chromatin and optimal origin firing in S phase.
Overall design CDC45 ChIP DNA purification and sequencing from untreated HCT116 cells (stably expressing WT or MUT-ORC1) in duplicate
Contributor(s) Mas AM, Goñi E, Huarte M
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Submission date Jun 23, 2022
Last update date Jun 06, 2023
Contact name Maite Huarte
Organization name CIMA
Street address c/ Avd Pio XII, 55
City Pamplona
State/province Navarra
ZIP/Postal code 31008
Country Spain
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (8)
GSM6265475 WT1_S4
GSM6265476 WT1_S25
GSM6265477 MUT1_S7
This SubSeries is part of SuperSeries:
GSE173452 ORC1 binds to cis-transcribed RNAs for efficient activation of human origins
BioProject PRJNA852271

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Supplementary file Size Download File type/resource 79.5 Mb (ftp)(http) BW 154.8 Mb (ftp)(http) BW 66.6 Mb (ftp)(http) BW 51.4 Mb (ftp)(http) BW
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Processed data are available on Series record

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