|
| Status |
Public on Oct 04, 2022 |
| Title |
PTEN directs developmental and metabolic signaling for innate-like T cells fate and tissue homeostasis [scRNA-seq and scTCR-seq Exp2] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
|
| Summary |
Developmental and metabolic signaling networks underpinning type-17 cell fate decisions in dictating tissue homeostasis versus tissue homeostasis
|
| |
|
| Overall design |
We used scRNA-seq and scTCR-seq to profile pre-selection DP, post-selection DP, and CCR6+CD127+TCRb+ thymocytes of WT and Cd4CrePtenfl/fl mice
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| |
|
| Contributor(s) |
Risch I, Sun Y, Shi H, Chi H |
| Citation(s) |
36302969 |
| |
| Submission date |
Jun 20, 2022 |
| Last update date |
Jan 03, 2023 |
| Contact name |
Hongbo Chi |
| E-mail(s) |
hongbo.chi@stjude.org
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Immunology
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE179512 |
Thymic development of type-17 innate-like T cells depends on PTEN |
|
| Relations |
| BioProject |
PRJNA851033 |
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