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Series GSE206342 Query DataSets for GSE206342
Status Public on Jun 16, 2023
Title Identification of KPNA2 targets by RNA-Seq in osteosarcoma
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Despite recent advances, the poor outcomes in osteosarcoma suggest that novel therapeutic targets are needed. Karyopherin alpha 2 (KPNA2) is a nuclear import factor, which functions as an oncogene in many cancers. However, the role of KPNA2 in osteosarcoma and its mechanism of action are still unclear. To identify gene signatures that play a role in metastasis, we performed RNA-Seq of gene expression profiling on U2OS cells treated with siKPNA2 and siNC (in triplicate for each group).
 
Overall design U2OS cells were treated with siKPNA2 and siNC (in triplicate for each group).
 
Contributor(s) Zhou S, Liu R
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Submission date Jun 17, 2022
Last update date Jun 16, 2023
Contact name Sheng Zhou
E-mail(s) zhou415098@sina.com
Phone +8615007159325
Organization name The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University
Street address 29 Xinlong Lane
City Changzhou
State/province Jiangsu
ZIP/Postal code 213003
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (6)
GSM6251642 KPNA2_1_Si
GSM6251643 KPNA2_2_Si
GSM6251644 KPNA2_3_Si
Relations
BioProject PRJNA850355

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE206342_U2OS_genes_count_fpkm_matrix.txt.gz 8.0 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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