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| Status |
Public on May 30, 2022 |
| Title |
Interplay of CodY and CcpA in regulating central metabolism and biofilm formation in Staphylococcus aureus |
| Organism |
Staphylococcus aureus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To determine the contribution and interplay of these two regulators in modulating central metabolism, virulence, and biofilm development we constructed and characterized codY ccpA double mutant in S. aureus UAMS-1.
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| Overall design |
Comparative gene expression profiling analysis if RNA-seq data for UAMS-1 WT, codY, ccpA, and CodYCcpA
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| Contributor(s) |
Bulock L, Ahn J, Shinde D, Pandey S, Sarmiento C, Thomas VC, Bayles KW, Sadykov MR |
| Citation(s) |
35735992 |
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| Submission date |
May 26, 2022 |
| Last update date |
Aug 29, 2022 |
| Contact name |
MARAT SADYKOV |
| E-mail(s) |
msadykov@unmc.edu
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| Phone |
4025594953
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| Organization name |
University of Nebraska Medical Center
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| Department |
Pathology and Microbiology
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| Street address |
985900 Nebraska Medical Center
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| City |
Omaha |
| State/province |
Nebraska |
| ZIP/Postal code |
68198 |
| Country |
USA |
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| Platforms (1) |
| GPL28116 |
NextSeq 550 (Staphylococcus aureus) |
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| Samples (24)
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| GSM6199276 |
UAMS-1 codY, 3h, sample 1 |
| GSM6199277 |
UAMS-1 codY, 3h, sample 2 |
| GSM6199278 |
UAMS-1 codY, 3h, sample 3 |
| GSM6199279 |
UAMS-1 ccpA, 3h, sample 1 |
| GSM6199280 |
UAMS-1 ccpA, 3h, sample 2 |
| GSM6199281 |
UAMS-1 ccpA, 3h, sample 3 |
| GSM6199282 |
UAMS-1 codYccpA, 3h, sample 1 |
| GSM6199283 |
UAMS-1 codYccpA, 3h, sample 2 |
| GSM6199284 |
UAMS-1 codYccpA, 3h, sample 3 |
| GSM6199285 |
UAMS-1 WT, 6h, sample 1 |
| GSM6199286 |
UAMS-1 WT, 6h, sample 2 |
| GSM6199287 |
UAMS-1 WT, 6h, sample 3 |
| GSM6199288 |
UAMS-1 codY, 6h, sample 1 |
| GSM6199289 |
UAMS-1 codY, 6h, sample 2 |
| GSM6199290 |
UAMS-1 codY, 6h, sample 3 |
| GSM6199291 |
UAMS-1 ccpA, 6h, sample 1 |
| GSM6199292 |
UAMS-1 ccpA, 6h, sample 2 |
| GSM6199293 |
UAMS-1 ccpA, 6h, sample 3 |
| GSM6199294 |
UAMS-1 codYccpA, 6h, sample 1 |
| GSM6199295 |
UAMS-1 codYccpA, 6h, sample 2 |
| GSM6199296 |
UAMS-1 codYccpA, 6h, sample 3 |
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| Relations |
| BioProject |
PRJNA842676 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE204884_Table_S3.xlsx |
119.7 Kb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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