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| Status |
Public on Oct 17, 2023 |
| Title |
Profiling of IL-33 target genes incytotoxic T cells, T helper 1 and T helper 2 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To decipher the T cell subset-specific consequences of IL-33 sensing, we profiled early changes in transcriptional activity of in vitro differentiated CTLs, Th1 cells and Th2 cells upon short-term stimulation with IL-33.
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| Overall design |
Comparative gene expression profiling analysis of the effects of IL-33 on CTLs, Th1 and Th2 cells using RNA-Seq and single-cell RNA-Seq of WT- and Il1rl1-ExAB-KO CTLs after an acute LCMV infection.
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| Contributor(s) |
Brunner TM, Serve SG, Marx A, Dzamukova M, Duran N, Saikali P, Kommer C, Heinrich F, Durek P, Heinz GA, Höfer T, Mashreghi M, Pinschewer DD, Kühn R, Löhning M |
| Citation(s) |
38172258 |
| |
| Submission date |
May 24, 2022 |
| Last update date |
Feb 14, 2024 |
| Contact name |
Pawel Durek |
| E-mail(s) |
pawel.durek@drfz.de
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| Organization name |
Deutsches Rheuma-Forschungszentrum
|
| Street address |
Charitéplatz 1
|
| City |
Berlin |
| ZIP/Postal code |
10117 |
| Country |
Germany |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (27)
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| This SubSeries is part of SuperSeries: |
| GSE204695 |
A type 1 immunity-restricted promoter of the IL-33 receptor gene drives antiviral T cell responses |
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| Relations |
| BioProject |
PRJNA841972 |
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