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Series GSE202409 Query DataSets for GSE202409
Status Public on Nov 01, 2022
Title Effect of LUCAT1 depletion in THP-1 monocytes on gene expression
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary To investigate the effect of LUCAT1 depletion on gene expression after stimulation with LPS or infection with Sendai virus, RNA-seq on THP-1 control guide RNA and LUCAT1-deficient cells after stimulation.
 
Overall design LUCAT1-deficient cells were generated using CRISPR/Cas9 system and cells transduced with a non-targeting guide RNA were used as a control. Two independent experiments per treatment and per genotype were performed.
 
Contributor(s) Fitzgerald KA, Vierbuchen T
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Submission date May 06, 2022
Last update date Nov 01, 2022
Contact name Katherine A Fitzgerald
E-mail(s) kate.fitzgerald@umassmed.edu
Phone 5088566518
Organization name Umass Chan Medical
Department Medicine
Street address 364 Plantation Street
City Worcester
State/province Massachusetts
ZIP/Postal code 01605
Country USA
 
Platforms (1)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (16)
GSM6119063 THP-1, control gRNA (NTC), non-treated, biol rep 1 [NTC_NT_rep1]
GSM6119064 THP-1, control gRNA (NTC), non-treated, biol rep 2 [NTC_NT_rep2]
GSM6119065 THP-1, control gRNA (NTC), LPS 1h, biol rep 1 [NTC_LPS_1h_rep1]
Relations
BioProject PRJNA835864

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE202409_DESeq_comparisons.csv.gz 132.8 Kb (ftp)(http) CSV
GSE202409_genes_expression_raw_count.tsv.gz 2.2 Mb (ftp)(http) TSV
GSE202409_genes_expression_tpm.tsv.gz 2.2 Mb (ftp)(http) TSV
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Raw data are available in SRA
Processed data are available on Series record

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