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Series GSE201686 Query DataSets for GSE201686
Status Public on Sep 28, 2022
Title Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [Rat_ChIP-seq]
Organism Rattus norvegicus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD).
 
Overall design ChIP-seq of rat brain tissues
 
Contributor(s) Cheng F, Riess O
Citation(s) 35015830
Submission date Apr 27, 2022
Last update date Sep 30, 2022
Contact name Fubo Cheng
E-mail(s) fubo.cheng@med.uni-tuebingen.de
Organization name University of Tuebingen
Department Institute of Medical Genetics and Applied Genomics
Street address Calwerstrasse 7
City Tuebingen
ZIP/Postal code 72076
Country Germany
 
Platforms (1)
GPL25947 Illumina NovaSeq 6000 (Rattus norvegicus)
Samples (9)
GSM6069493 SNCA TG Input
GSM6069494 SNCA TG-L Input
GSM6069495 SNCA EnKO Input
This SubSeries is part of SuperSeries:
GSE141278 Transcription regulation of SNCA by dystonia type 6 gene product THAP1
Relations
BioProject PRJNA832672

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE201686_RAW.tar 43.2 Mb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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