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Series GSE201686 Query DataSets for GSE201686
Status Public on Sep 28, 2022
Title Transcription regulation of SNCA by dystonia type 6 gene product THAP1 [Rat_ChIP-seq]
Organism Rattus norvegicus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The predominantly function of THAP1 has been defined as a transcription factor, but how it regulates gene expression in human neurons is not well understood. Here, we found that THAP1 is able to regulate the expression of alpha-synuclein (SNCA), a key protein in Parkinson’s disease (PD).
Overall design ChIP-seq of rat brain tissues
Contributor(s) Cheng F, Riess O
Citation(s) 35015830
Submission date Apr 27, 2022
Last update date Sep 30, 2022
Contact name Fubo Cheng
Organization name University of Tuebingen
Department Institute of Medical Genetics and Applied Genomics
Street address Calwerstrasse 7
City Tuebingen
ZIP/Postal code 72076
Country Germany
Platforms (1)
GPL25947 Illumina NovaSeq 6000 (Rattus norvegicus)
Samples (9)
GSM6069493 SNCA TG Input
GSM6069494 SNCA TG-L Input
GSM6069495 SNCA EnKO Input
This SubSeries is part of SuperSeries:
GSE141278 Transcription regulation of SNCA by dystonia type 6 gene product THAP1
BioProject PRJNA832672

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE201686_RAW.tar 43.2 Mb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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