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Series GSE200647 Query DataSets for GSE200647
Status Public on May 16, 2022
Title DNA methylation analysis of glioblastomas harboring FGFR3-TACC3 fusions identifies a methylation subclass with better patient survival.
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Genomewide DNA methylation array profiling of 244 gliobastoma and ganglioglioma samples to study FGFR3-TACC3 gene fusions and resolved into a new entity, glioblastoma IDH-wildtype, FGFR3-TACC3 fusion postive methylation outlier group (GBM-F3T3-O). GBM-F3T3-O showed a unique methylation profile and better survival than other glioblastoma patients. The methylation idat profiles were provided here.
 
Overall design Bisulfite converted genomic DNA extracted from tumor samples was hybridized to Illumina Infinium EPIC Human DNA Methylation Beadchips
Please note that the processed data files contains total 276 data columns, including 32 samples (columns) whose the raw data was provided by authors of paper PMID: 33168106.
 
Contributor(s) Wu Z, Aldape K
Citation(s) 35567606
Submission date Apr 11, 2022
Last update date May 18, 2022
Contact name Zhichao Wu
Organization name NIH/NCI
Department Center for Cancer Research
Lab Laboratory of Pathology
Street address BG 10 RM 4A31 MSC 1500, 10 CENTER DR
City BETHESDA
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL21145 Infinium MethylationEPIC
Samples (244)
GSM6040552 GBM [F1]
GSM6040553 GBM [F10]
GSM6040554 GBM-F3T3-O [F11]
Relations
BioProject PRJNA825641

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE200647_01.F3T3.preprocessFunnorm.betas.txt.gz 1.6 Gb (ftp)(http) TXT
GSE200647_01.F3T3.preprocessFunnorm.detectionPvalue.txt.gz 457.2 Mb (ftp)(http) TXT
GSE200647_RAW.tar 3.5 Gb (http)(custom) TAR (of IDAT)
Processed data are available on Series record

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