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Series GSE199533 Query DataSets for GSE199533
Status Public on Jan 06, 2024
Title Circulating isomiRs May Be Superior Biomarkers Compared to Their Corresponding Canonical miRNAs: A Pilot Biomarker Study of Using isomiR-ome to Detect Coronary Calcium-Based Cardiovascular Risk in Patients with NAFLD
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD). Yet clinically, distinguishing between NAFLD patients with average CV risk from those at elevated risk is not easily achieved by traditional CV risk factors and clinically-based scoring systems. Here we hypothesize that in-depth analysis of circulating miRNAs can identify strong putative biomarkers for the degree of CV risk among patients with NAFLD
Overall design Plasma miRNAs of 12 NAFLD patients were sequenced by next-generation sequencing (NGS).
Contributor(s) Makarenkov N, Yoel U, Haim Y, Bhandarkar NS, Shalev A, Shelef I, Liberty IF, Arie G, Yardeni D, Rudich A, Etzion O, Veksler-Lublinsky I
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Submission date Mar 28, 2022
Last update date Jan 06, 2024
Contact name Nataly Makarenkov
Organization name Ben Gurion University
Street address David Ben Gurion Blvd 1
City Be'er Sheva
State/province N/A
ZIP/Postal code 84105
Country Israel
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (13)
GSM5974770 patient1
GSM5974771 patient2
GSM5974772 patient3
BioProject PRJNA820636

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SOFT formatted family file(s) SOFTHelp
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Supplementary file Size Download File type/resource
GSE199533_NAFLD_isomiR_sample_miRge3.gff.gz 6.1 Mb (ftp)(http) GFF
GSE199533_NAFLD_miRNA_RPM.csv.gz 36.3 Kb (ftp)(http) CSV
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