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Status |
Public on Mar 01, 2024 |
Title |
TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf (Seq01, bulk-RNAseq) |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Naive murine CD4+ T cells were cultured under different polarizing conditions in 96-well plates coated with anti-CD3/anti-CD28 for 3.5 days, sorted by flow cytometry, and subjected to bulk RNA-seq.
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Overall design |
Seq01: bulk RNA-seq: Th1, Tfh(anti-TGF-β) = TfhA, Tfh(5 ng/ml TGF-β) = Tfh(5)
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Web link |
https://www.science.org/doi/10.1126/sciimmunol.add4818
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Contributor(s) |
Baumjohann D, Chang Y |
Citation(s) |
38427718 |
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Submission date |
Mar 10, 2022 |
Last update date |
Mar 04, 2024 |
Contact name |
Dirk Baumjohann |
E-mail(s) |
dirk.baumjohann@uni-bonn.de
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Organization name |
University Hospital Bonn
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Department |
Medical Clinic III
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Lab |
Baumjohann Lab
|
Street address |
Venusberg-Campus 1
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City |
Bonn |
State/province |
NRW |
ZIP/Postal code |
53127 |
Country |
Germany |
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Platforms (1) |
GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
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Samples (14)
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Relations |
BioProject |
PRJNA814700 |