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Series GSE198329 Query DataSets for GSE198329
Status Public on Jul 21, 2022
Title 16S V3-V4 -based microbial profiling of matched healthy and inflamed ileal mucosa from patients affected by Crohn’s disease (set 2)
Organism Homo sapiens
Experiment type Other
Summary Crohn’s Disease (CD) pathogenesis is still unclear. Disorders in the mucosal immunoregulation and its crosstalk with the microbiota may represent an important component in tissue injury. We aimed to characterize the molecular immune response distribution within the ileal layers ( mucosa, submucosa and serosa) and to evaluate the correlated microbiota in pathological/healthy settings comparing first surgery/relapse clinical conditions.
Overall design 26 matched pairs of paraffin-embedded ileal tissue specimens was extracted and 16S rDNA amplicons (V3-V4 region)
Contributor(s) Ramazzotti M, Amedei A
Citation(s) 35967326
Submission date Mar 10, 2022
Last update date Aug 24, 2022
Contact name Matteo Ramazzotti
Organization name University of Florence
Department Experimental and Clinical Biomedical Sciences
Street address viale Morgagni 50
City Firenze
ZIP/Postal code 50134
Country Italy
Platforms (1)
GPL15520 Illumina MiSeq (Homo sapiens)
Samples (26)
GSM5945163 Notinflamed tissue from patient 1
GSM5945164 Notinflamed tissue from patient 2
GSM5945165 Notinflamed tissue from patient 3
BioProject PRJNA814642

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE198329_otu_tax.txt.gz 23.7 Kb (ftp)(http) TXT
GSE198329_otus.fasta.gz 132.8 Kb (ftp)(http) FASTA
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Raw data are available in SRA
Processed data are available on Series record

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