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Series GSE19815 Query DataSets for GSE19815
Status Public on Apr 06, 2010
Title Oncogenic Functions of the Transcription Factor LSF
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Overexpression of LSF in less aggressive hepatocellular carcinoma (HCC) cells resulted in highly aggressive, angiogenic and multi-organ metastatic tumors while inhibition of LSF significantly abrogated growth and metastasis of highly aggressive HCC cells in nude mice.
We used microarrays to identify the downstream genes mediating the effects of LSF in HCC cells.
Overall design Gene expression profiles were compared between Control-8 and LSF-17 clones of HepG3 cells.
Contributor(s) Sarkar D, Dumur CI
Citation(s) 20404171
Submission date Jan 08, 2010
Last update date Dec 06, 2018
Contact name Devanand Sarkar
Organization name Virginia Commonwealth University
Department Department of Human and Molecular Genetics
Lab VCU Institute of Molecular Medicine
Street address 1220 E Broad St, Room 7044
City Richmond
State/province VA
ZIP/Postal code 23298
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (6)
GSM494820 Control-8 clone, biological rep1
GSM494821 Control-8 clone, biological rep2
GSM494822 Control-8 clone, biological rep3
BioProject PRJNA122087

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE19815_RAW.tar 20.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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