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Series GSE197786 Query DataSets for GSE197786
Status Public on Oct 26, 2022
Title Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis [scRNA-seq]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In this study, using the mouse molar as a model, we took advantage of single-cell transcriptome profiling, lineage tracing and transgenic mouse models to interrogate the cellular heterogeneity and gene regulatory networks (GRNs) of postmigratory CNCCs.In this study, we have put together a dynamic spatiotemporal single-cell regulatory atlas and revealed the landscape of transcriptional heterogeneity and defined the cellular domains during the progression of cranial neural crest cell (CNCC)-derived dental lineage diversification. Importantly, we identified cell type-specific gene regulatory networks (GRNs) during CNCC-derived dental lineage development.
 
Overall design Single-nuclei transcriptomes were obtained from trigemial ganglion of one-month-old mice
 
Contributor(s) Pei F
Citation(s) 36670126
Submission date Mar 02, 2022
Last update date Feb 08, 2023
Contact name Fei Pei
E-mail(s) fp_191@usc.edu
Phone 2132454762
Organization name USC
Street address 2250 Alcazar St
City Los Angeles
State/province CA
ZIP/Postal code 90033
Country USA
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (1)
GSM5930412 T1
This SubSeries is part of SuperSeries:
GSE197787 Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis.
Relations
BioProject PRJNA812042

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE197786_RAW.tar 75.9 Mb (http)(custom) TAR (of MTX, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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