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Series GSE196949 Query DataSets for GSE196949
Status Public on May 23, 2022
Title Lung epithelial CYP1 activity regulates aryl hydrocarbon receptor dependent allergic airway inflammation
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Transcriptional analysis of human lung epithelial cells indicates a functional link of AhR to barrier protection/inflammatory mediator signaling upon allergen challenge.
Overall design Primary normal bronchial epithelial cells (NHBEs) were incubated eihter medium or AhR inhibitor CH223191 (1µM/mL) for 2 hours, afterwards with IL-4 (50ng/mL) and house dust mite extract (40µg/mL) for 6 hours.
Contributor(s) Alessandrini F, de Jong R, Wimmer M, Maier A, Fernandez I, Hils M, Buters J, Biedermann T, Zissler UM, Hoffmann C, Esser-von Bieren J, Schmidt-Weber CB, Ohnmacht C
Citation(s) 35734174
Submission date Feb 17, 2022
Last update date Jun 30, 2022
Contact name Ulrich M Zissler
Phone +49 (0)89 4140 3472
Organization name Technical University of Munich & Helmholtz Center Munich
Department Center of Allergy & Environment (ZAUM)
Lab Airway Immunology
Street address Biedersteiner Str. 29
City Munich
ZIP/Postal code 80802
Country Germany
Platforms (1)
GPL13607 Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version)
Samples (29)
GSM5905574 NHBE Medium [NHBE_01]
GSM5905575 NHBE Medium [NHBE_02]
GSM5905576 NHBE Medium [NHBE_03]
BioProject PRJNA808035

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE196949_RAW.tar 358.9 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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