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Status |
Public on Jun 16, 2022 |
Title |
Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells [CUT&TAG] |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
We profiled medullary thymic epithelial cells by CUT&Tag to investigate mechanisms of T-cell tolerance.
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Overall design |
CUT&Tag of mTECs
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Contributor(s) |
Michelson DA, Mathis D, Benoist C |
Citation(s) |
35714609 |
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Submission date |
Jan 23, 2022 |
Last update date |
Aug 30, 2022 |
Contact name |
CBDM Lab |
E-mail(s) |
cbdm@hms.harvard.edu
|
Phone |
617-432-7747
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Organization name |
Harvard Medical School
|
Department |
Microbiology and Immunobiology
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Lab |
CBDM
|
Street address |
77 Avenue Louis Pasteur
|
City |
Boston |
State/province |
MA |
ZIP/Postal code |
02215 |
Country |
USA |
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Platforms (3) |
GPL16417 |
Illumina MiSeq (Mus musculus) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (19)
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This SubSeries is part of SuperSeries: |
GSE194253 |
Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells |
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Relations |
BioProject |
PRJNA799776 |