|
| Status |
Public on Feb 06, 2022 |
| Title |
CRISPR and biochemical screens Identify MAZ as a co-factor in CTCF-mediated insulation at Hox Clusters [CRISPR_set8] |
| Organisms |
Mus musculus; synthetic construct |
| Experiment type |
Other
|
| Summary |
In this experiment, we sought to analyze the genes positively or negatively selected during differentiation of mouse embryonic stem cells (ESCs) into cervical motor neurons (MNs) with particular focus on the genes enriched for CTCF boundary disruption at HoxA cluster
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| |
|
| Overall design |
Examination of the genes positively or negatively selected in embryonic stem cells and cervical motor neurons using CRISPR loss-of-function screens, with particular focus on the genes enriched for CTCF boundary disruption at HoxA cluster
|
| |
|
| Contributor(s) |
Reinberg D |
| Citation(s) |
35145304 |
| |
| Submission date |
Dec 21, 2021 |
| Last update date |
Feb 15, 2022 |
| Contact name |
Danny Reinberg |
| E-mail(s) |
Danny.Reinberg@nyulangone.org
|
| Phone |
212-263-9036
|
| Organization name |
New York University School of Medicine
|
| Department |
Biochemistry
|
| Lab |
Reinberg Lab
|
| Street address |
522 First Avenue, 2nd floor, Room 211
|
| City |
New York |
| State/province |
New York |
| ZIP/Postal code |
10016 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL17769 |
Illumina MiSeq (synthetic construct) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (13)
|
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| This SubSeries is part of SuperSeries: |
| GSE157139 |
CRISPR and biochemical screens identify MAZ as a co-factor in CTCF-mediated insulation at Hox clusters |
|
| Relations |
| BioProject |
PRJNA791399 |
| SRA |
SRP351995 |
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