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Series GSE189929 Query DataSets for GSE189929
Status Public on Jun 15, 2024
Title The role of RPA1 in T cells [thymus]
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary As a single strand DNA binding protein, RPA1 participates in various cellular processes including DNA replication and DNA repair. However, the role of RPA1 in T cells is largely unknown. We generated a mouse model in which RPA1 was specifically deleted in T cells. Through single cell RNA sequencing, we reveal the immune landscape in RPA1 conditional knockout mice.
Overall design Study of immune cells in thymus from WT or RPA1 conditional knockout mice using 10x scRNA-seq technologies.
Contributor(s) Song J, Lu D, Zhang X
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Submission date Dec 01, 2021
Last update date Jun 15, 2024
Contact name Jia Song
Phone +18830053918
Organization name Peking University
Street address Peking University School of Medicine, 38 Xueyuan Road, Haidian District, Beijing
City Beijing
State/province China
ZIP/Postal code 100080
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (2)
GSM5710063 thymus, WT
GSM5710064 thymus, Rpa1 KO
BioProject PRJNA785154
SRA SRP348994

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE189929_RAW.tar 87.3 Mb (http)(custom) TAR (of MTX, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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